Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 15/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | CCR9 | P51686 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738720 | 0.89 | NOD2 (0.49) | CCR2PTGESABCB1 | |
| SCHEMBL4098695 | 0.83 | CCR2 (0.51) | CCR2ABCB11PTGESCCR9 | |
| SCHEMBL6091132 | 0.79 | PTGES (0.55) | CCR2PTGESSERPINE1 | |
| SCHEMBL6091214 | 0.79 | PTGES (0.51) | CCR2PTGESSERPINE1 | |
| SCHEMBL7245116 | 0.78 | CCR2 (0.79) | CCR2ABCB11SERPINE1 | |
| SCHEMBL2000903 | 0.78 | CCR2 (0.75) | CCR2ABCB11CCR9 | |
| SCHEMBL4097358 | 0.77 | CCR2 (0.44) | CCR2PTGESCCR9 | |
| SCHEMBL6093568 | 0.77 | PTGES (0.54) | CCR2PTGESSERPINE1 | |
| SCHEMBL3967526 | 0.77 | CCR2 (1.00) | CCR2ABCB11CCR9 | |
| SCHEMBL27658570 | 0.77 | CCR2 (0.82) | CCR2ABCB11CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |