Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR1F | P30939 | 3/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.41 |
| ▸ | CCR2 | P41597 | 3/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4767261 | 0.85 | GPR119 (0.53) | CTSSKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL373860 | 0.85 | KDM4E (0.60) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL27926316 | 0.82 | HSD11B1 (0.49) | CTSSKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL5750470 | 0.81 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL5749634 | 0.81 | HTR1D (0.42) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL18324777 | 0.78 | KDM4E (0.69) | CTSSKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL31001677 | 0.77 | GPR119 (0.53) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL12327686 | 0.77 | GPR119 (0.53) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL2064650 | 0.76 | HTR1D (0.59) | CTSSKDM4EHTR1DHTR1AHTR1F | |
| SCHEMBL27687984 | 0.74 | KDM4E (0.64) | KDM4EBRD4ALDH1A1POLBCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497292-B1 | AZAINDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2006-06-14 | — | — | EP | claimed |