Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667019 | 0.90 | KCNH2 (0.45) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL5750711 | 0.88 | KCNH2 (0.40) | MEN1KMT2AKCNH2 | |
| SCHEMBL5765739 | 0.88 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL14573152 | 0.86 | KCNH2 (0.44) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL5748821 | 0.84 | KCNH2 (0.39) | HPGDMEN1KMT2AKCNH2 | |
| SCHEMBL5751255 | 0.81 | KCNH2 (0.38) | MEN1KMT2AKCNH2 | |
| SCHEMBL5750809 | 0.80 | KCNH2 (0.38) | MEN1KMT2AKCNH2 | |
| SCHEMBL5749450 | 0.80 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL5747711 | 0.80 | KCNH2 (0.38) | MEN1KMT2AKCNH2POLB | |
| SCHEMBL5656474 | 0.80 | HTR1A (0.47) | ALDH1A1LMNAHPGDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419155-B1 | PIPERIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | claimed |