Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14573152 | 0.90 | KCNH2 (0.44) | ALDH1A1LMNAKCNH2NPC1RAB9A | |
| SCHEMBL5751074 | 0.88 | NPC1 (0.41) | ALDH1A1LMNAKCNH2NPC1RAB9A | |
| SCHEMBL5764669 | 0.88 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5767030 | 0.86 | SLC2A1 (0.43) | KCNH2 | |
| SCHEMBL5764977 | 0.86 | HTR1D (0.53) | ALDH1A1KCNH2HTR1DHTR1AHTR1B | |
| SCHEMBL6667019 | 0.86 | KCNH2 (0.45) | ALDH1A1LMNAKCNH2NPC1RAB9A | |
| SCHEMBL5656474 | 0.84 | HTR1A (0.47) | ALDH1A1LMNAKCNH2HPGDHTR1D | |
| SCHEMBL5762645 | 0.81 | KCNH2 (0.53) | ALDH1A1LMNAKCNH2NPC1RAB9A | |
| SCHEMBL5765126 | 0.80 | SLC2A1 (0.43) | KCNH2 | |
| SCHEMBL14573142 | 0.78 | KCNH2 (0.44) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392686-B1 | BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-10-18 | — | — | EP | claimed |