Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
| ▸ | POLQ | O75417 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755917 | 0.85 | EPHX2 (0.51) | PPARGPPARAEPHX2MDM2MAOB | |
| SCHEMBL9492298 | 0.83 | PPARG (0.57) | PPARGPPARAEPHX2POLQ | |
| SCHEMBL5753316 | 0.76 | PPARG (0.45) | PPARGPPARAEPHX2POLQ | |
| SCHEMBL7375299 | 0.76 | EPHX2 (0.59) | PPARGPPARAEPHX2POLQCTNNB1 | |
| SCHEMBL10660853 | 0.75 | PPARG (0.47) | PPARGPPARAEPHX2MDM2POLQ | |
| SCHEMBL10885169 | 0.75 | PPARG (0.50) | PPARGPPARAEPHX2POLQ | |
| SCHEMBL7123489 | 0.74 | GSK3B (0.49) | PPARGPPARAEPHX2MDM2 | |
| SCHEMBL6695640 | 0.74 | PPARG (0.51) | PPARGPPARAEPHX2POLQCTNNB1 | |
| SCHEMBL16815322 | 0.74 | PPARG (0.55) | PPARGPPARAEPHX2POLQMAOB | |
| SCHEMBL27761205 | 0.74 | MAOB (0.49) | PPARGPPARAEPHX2POLQCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | PPARG 905/4885PPARA 708/4885EPHX2 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.