Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752236 | 0.80 | IDO1 (0.41) | PPARGPPARATACR1SLC6A2SLC6A4 | |
| SCHEMBL5747726 | 0.77 | FFAR1 (0.42) | PPARGPPARAEPHX2AKR1C3AKR1C2 | |
| SCHEMBL5751195 | 0.76 | PPARG (0.47) | PPARGPPARAPOLQEPHX2 | |
| SCHEMBL5749682 | 0.76 | PPARG (0.44) | PPARGPPARAEPHX2AKR1C3AKR1C2 | |
| SCHEMBL5751624 | 0.76 | PPARG (0.44) | PPARGPPARAEPHX2AKR1C3AKR1C2 | |
| SCHEMBL5752733 | 0.75 | KMT2A (0.48) | PPARGPPARAAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL16815322 | 0.75 | PPARG (0.55) | PPARGPPARAPOLQEPHX2SLC6A2 | |
| SCHEMBL9492298 | 0.75 | PPARG (0.57) | PPARGPPARAPOLQEPHX2SLC6A2 | |
| SCHEMBL5751805 | 0.74 | SLC1A1 (0.47) | PPARGPPARATACR1SLC6A2SLC6A4 | |
| SCHEMBL7375299 | 0.74 | EPHX2 (0.59) | PPARGPPARAPOLQEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | PPARG 905/4885PPARA 708/4885POLQ 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.