Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.59 |
| ▸ | PPARG | P37231 | 8/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | POLQ | O75417 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492298 | 0.87 | PPARG (0.57) | EPHX2PPARGPPARAPOLQ | |
| SCHEMBL16815322 | 0.84 | PPARG (0.55) | EPHX2PPARGPPARAPOLQ | |
| SCHEMBL42976 | 0.83 | PPARG (0.53) | EPHX2PPARGPPARAPOLQ | |
| SCHEMBL42975 | 0.83 | PPARG (0.53) | EPHX2PPARGPPARAPOLQ | |
| SCHEMBL503201 | 0.83 | PPARG (0.53) | EPHX2PPARGPPARAPOLQ | |
| SCHEMBL14208224 | 0.83 | PPARG (0.62) | EPHX2PPARGPPARAPOLQ | |
| SCHEMBL29410813 | 0.83 | PPARG (0.53) | EPHX2PPARGPPARAPOLQ | |
| SCHEMBL7508666 | 0.82 | EPHX2 (0.53) | EPHX2PPARGPPARAPOLQCTNNB1 | |
| SCHEMBL27933828 | 0.80 | PPARG (0.51) | EPHX2PPARGPPARAPOLQ | |
| SCHEMBL27933826 | 0.80 | PPARG (0.51) | EPHX2PPARGPPARAPOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870183-A | RENIN INHIBITORS, HYPOTENSIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0252727-A1 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-01-13 | — | — | EP | disclosed |