Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 8/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754442 | 0.82 | TXNRD1 (0.47) | TXNRD1TP53MAPTHTTPOLB | |
| SCHEMBL5753176 | 0.82 | TXNRD1 (0.54) | TXNRD1MAPTHTTMAPK1NPSR1 | |
| SCHEMBL2421463 | 0.80 | ALDH1A1 (0.64) | TXNRD1MAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL5752857 | 0.80 | ALDH1A1 (0.64) | TXNRD1MAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL6973245 | 0.78 | SMN1; SMN2 (0.44) | TP53MAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL5754970 | 0.77 | TXNRD1 (0.48) | TXNRD1MAPTPOLBMAPK1NPSR1 | |
| SCHEMBL14334303 | 0.77 | TXNRD1 (0.51) | TXNRD1MAPTPOLBMAPK1NPSR1 | |
| SCHEMBL26087023 | 0.74 | TXNRD1 (0.42) | TXNRD1MAPTHTTPOLBMAPK1 | |
| Hydrochloric Acid SCHEMBL5220902 | 0.74 | TXNRD1 (0.49) | TXNRD1MAPTHTTPOLBMAPK1 | |
| SCHEMBL2270765 | 0.74 | SMPD3 (0.43) | MAPTHTTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1336606-B1 | 6-Alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibers | OREAL (FR) | 2006-12-27 | — | — | EP | disclosed |
| EP-1336606-A1 | 6-Alkoxy-2,3-diaminopyridine couplers for dying keratin fibers | L'OREAL (FR) | 2003-08-20 | — | — | EP | disclosed |