Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 18/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751204 | 0.82 | TXNRD1 (0.52) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL5752857 | 0.78 | ALDH1A1 (0.64) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL2421463 | 0.78 | ALDH1A1 (0.64) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL5754970 | 0.78 | TXNRD1 (0.48) | TXNRD1MAPTMAPK1NPSR1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL5220902 | 0.78 | TXNRD1 (0.49) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL26089650 | 0.77 | POLB (0.48) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL26089775 | 0.77 | POLB (0.48) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL8569551 | 0.77 | TXNRD1 (0.50) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL5753875 | 0.76 | SIRT6 (0.54) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL30435070 | 0.76 | SIRT6 (0.54) | TXNRD1S1PR4MAPTS1PR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1336606-B1 | 6-Alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibers | OREAL (FR) | 2006-12-27 | — | — | EP | disclosed |
| US-6916345-B2 | 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-07-12 | — | — | US | disclosed |
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | disclosed |
| EP-1336606-A1 | 6-Alkoxy-2,3-diaminopyridine couplers for dying keratin fibers | L'OREAL (FR) | 2003-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | KRT18, DSP, DPYD | TXNRD1 1135/4885S1PR4 3918/4885MAPT 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.