Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862883 | 0.90 | L3MBTL1 (0.57) | MAPTL3MBTL1ATMALDH1A1CCR8 | |
| Hydrochloric Acid SCHEMBL28818373 | 0.89 | L3MBTL1 (0.56) | MAPTL3MBTL1ATMALDH1A1CCR8 | |
| SCHEMBL21593409 | 0.81 | L3MBTL1 (0.57) | MAPTL3MBTL1ATMALDH1A1CCR8 | |
| SCHEMBL3548161 | 0.81 | L3MBTL1 (0.57) | MAPTL3MBTL1ATMALDH1A1CCR8 | |
| SCHEMBL21593413 | 0.81 | L3MBTL1 (0.57) | MAPTL3MBTL1ATMALDH1A1CCR8 | |
| SCHEMBL29198358 | 0.81 | L3MBTL1 (0.57) | MAPTL3MBTL1ATMALDH1A1CCR8 | |
| SCHEMBL3551153 | 0.81 | L3MBTL1 (0.57) | MAPTL3MBTL1ATMALDH1A1CCR8 | |
| SCHEMBL5752863 | 0.81 | L3MBTL1 (0.48) | MAPTL3MBTL1ATMALDH1A1CCR8 | |
| Hydrochloric Acid SCHEMBL28818356 | 0.80 | L3MBTL1 (0.56) | MAPTL3MBTL1ATMALDH1A1CCR8 | |
| SCHEMBL6506401 | 0.80 | USP30 (0.55) | L3MBTL1ATMALDH1A1CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646621-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | Abbott Laboratories (US) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005007642-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | ABBOTT LABORATORIES (US) | 2005-01-27 | — | — | WO | disclosed |