Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213748 | 0.80 | PKM (0.49) | PKMCA2LMNACA12CA1 | |
| SCHEMBL2213839 | 0.79 | PKM (0.53) | PKMCA2LMNACA12CA1 | |
| SCHEMBL491041 | 0.78 | ALDH1A1 (0.40) | PKMCA2LMNACA12CA1 | |
| SCHEMBL5449778 | 0.78 | ALOX5 (0.35) | CA2LMNAALDH1A1GAABCL2L1 | |
| SCHEMBL2211621 | 0.76 | KDM4E (0.52) | PKMCA2LMNACA12CA1 | |
| SCHEMBL3176164 | 0.75 | TDP1 (0.48) | CA2LMNACA1ALDH1A1PTGS2 | |
| SCHEMBL28053491 | 0.73 | CA12 (0.49) | PKMCA2LMNACA12CA1 | |
| SCHEMBL23530144 | 0.71 | TDP1 (0.47) | PKMCA2LMNACA12CA1 | |
| SCHEMBL5748837 | 0.70 | ALDH1A1 (0.34) | CA2LMNAALDH1A1BCL2L1MAPK1 | |
| SCHEMBL2268669 | 0.69 | KDM4E (0.44) | PKMCA2LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | claimed |