Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 7/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751613 | 0.82 | KCNN4 (0.39) | MDM2KCNN4CCR3 | |
| SCHEMBL6579476 | 0.80 | KCNN4 (0.40) | KCNN4TACR1 | |
| SCHEMBL5751768 | 0.76 | PTGDR2 (0.39) | KCNN4 | |
| SCHEMBL5752398 | 0.72 | MDM2 (0.41) | MDM2TACR1 | |
| SCHEMBL5752541 | 0.72 | MDM2 (0.41) | MDM2TACR1 | |
| SCHEMBL5752174 | 0.71 | CES2 (0.37) | — | |
| SCHEMBL15744030 | 0.70 | FADS1 (0.53) | MDM2FADS1 | |
| SCHEMBL15744028 | 0.70 | FADS1 (0.53) | MDM2FADS1 | |
| SCHEMBL20794196 | 0.70 | FADS1 (0.53) | MDM2FADS1 | |
| SCHEMBL15744012 | 0.69 | CETP (0.46) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | MDM2 3868/4885KCNN4 4807/4885TACR1 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.