Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 2/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754442 | 0.81 | TXNRD1 (0.47) | NPY5RMAPTHTTALDH1A1 | |
| SCHEMBL6973245 | 0.80 | SMN1; SMN2 (0.44) | NPY5RMAPTHIF1AHTTL3MBTL1 | |
| SCHEMBL2416519 | 0.78 | PDE10A (0.41) | NPY5RMAPTCCNKCDK12CDK2 | |
| SCHEMBL2270765 | 0.76 | SMPD3 (0.43) | MAPTHIF1AHTTL3MBTL1NPC1 | |
| SCHEMBL29985389 | 0.72 | NPY5R (0.41) | NPY5RMAPTHIF1AHTTL3MBTL1 | |
| SCHEMBL27092770 | 0.72 | NPY5R (0.41) | NPY5RMAPTHIF1AHTTL3MBTL1 | |
| SCHEMBL27092773 | 0.72 | NPY5R (0.41) | NPY5RMAPTHIF1AHTTL3MBTL1 | |
| SCHEMBL2266765 | 0.72 | CASP3 (0.44) | MAPTHTTL3MBTL1MAP2K7ALDH1A1 | |
| SCHEMBL2267089 | 0.70 | HTR2A (0.43) | HCRTR2HCRTR1 | |
| SCHEMBL5752945 | 0.70 | ALDH1A1 (0.45) | MAPTHTTL3MBTL1MAP2K7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1336606-B1 | 6-Alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibers | OREAL (FR) | 2006-12-27 | — | — | EP | claimed |
| EP-1336606-A1 | 6-Alkoxy-2,3-diaminopyridine couplers for dying keratin fibers | L'OREAL (FR) | 2003-08-20 | — | — | EP | claimed |
| EP-1336606-B1 | 6-Alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibers | OREAL (FR) | 2006-12-27 | — | — | EP | disclosed |
| EP-1336606-A1 | 6-Alkoxy-2,3-diaminopyridine couplers for dying keratin fibers | L'OREAL (FR) | 2003-08-20 | — | — | EP | disclosed |