Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | GHSR | Q92847 | 8/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757143 | 1.00 | ALDH1A1 (0.35) | ALDH1A1CACNA1BGHSRP2RX7KMT2A | |
| SCHEMBL5753219 | 0.94 | ALDH1A1 (0.34) | ALDH1A1CACNA1BGHSRP2RX7KMT2A | |
| SCHEMBL5755208 | 0.93 | CACNA1B (0.36) | ALDH1A1CACNA1BHPGD | |
| SCHEMBL5756531 | 0.91 | HTR2C (0.40) | — | |
| SCHEMBL5752525 | 0.90 | BACE1 (0.32) | ALDH1A1HPGD | |
| SCHEMBL5756377 | 0.89 | ALDH1A1 (0.34) | ALDH1A1CACNA1BP2RX7KMT2APOLB | |
| SCHEMBL5752573 | 0.88 | KDM4E (0.41) | ALDH1A1CACNA1BGHSRP2RX7KMT2A | |
| SCHEMBL5755757 | 0.88 | KDM4E (0.41) | ALDH1A1CACNA1BGHSRP2RX7KMT2A | |
| SCHEMBL5759242 | 0.88 | KDM4E (0.41) | ALDH1A1CACNA1BGHSRP2RX7KMT2A | |
| SCHEMBL5753729 | 0.88 | ALDH1A1 (0.36) | ALDH1A1CACNA1BP2RX7KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |