Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757143 | 0.90 | ALDH1A1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL5754339 | 0.90 | ALDH1A1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL5755208 | 0.89 | CACNA1B (0.36) | BACE1LMNAMAPTCTSCKDM4E | |
| SCHEMBL5755360 | 0.88 | LMNA (0.34) | BACE1LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL5753443 | 0.88 | GSK3B (0.33) | LMNAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5756531 | 0.87 | HTR2C (0.40) | — | |
| SCHEMBL5753447 | 0.86 | MEN1 (0.31) | LMNAMAPTMAPK1L3MBTL1TDP1 | |
| SCHEMBL5754943 | 0.86 | MEN1 (0.31) | LMNAMAPTMAPK1L3MBTL1TDP1 | |
| SCHEMBL5754373 | 0.86 | MAPT (0.32) | BACE1LMNAMAPTTDP1CTSC | |
| SCHEMBL5753219 | 0.84 | ALDH1A1 (0.34) | BACE1LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |