Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 17/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755208 | 0.92 | CACNA1B (0.36) | HTR2CHTR2BPTPN1 | |
| SCHEMBL5754339 | 0.91 | ALDH1A1 (0.35) | — | |
| SCHEMBL5757143 | 0.91 | ALDH1A1 (0.35) | — | |
| SCHEMBL5753816 | 0.89 | NPC1 (0.37) | — | |
| SCHEMBL5753832 | 0.87 | CACNA1B (0.36) | HTR2CHTR2B | |
| SCHEMBL5752525 | 0.87 | BACE1 (0.32) | — | |
| SCHEMBL5753443 | 0.86 | GSK3B (0.33) | — | |
| SCHEMBL5753219 | 0.85 | ALDH1A1 (0.34) | — | |
| SCHEMBL5754373 | 0.84 | MAPT (0.32) | — | |
| SCHEMBL5758360 | 0.83 | PSMB1 (0.45) | PTPN1PSMB1PSMB8PSMB9PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |