Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752956 | 0.79 | KDM4E (0.54) | KDM4EHTTCACNA1GSIGMAR1KCNH2 | |
| SCHEMBL10362355 | 0.77 | KDM4E (0.74) | KDM4EHTTSIGMAR1SLC6A3 | |
| Hydrochloric Acid SCHEMBL7299429 | 0.76 | KDM4E (0.76) | KDM4EHTTSIGMAR1SLC6A3 | |
| SCHEMBL8725812 | 0.74 | SIGMAR1 (0.75) | KDM4EHTTSIGMAR1 | |
| SCHEMBL7423189 | 0.71 | SIGMAR1 (0.69) | KDM4EHTTSIGMAR1 | |
| SCHEMBL8029920 | 0.70 | LTA4H (0.65) | KDM4EHTTSIGMAR1 | |
| SCHEMBL8035741 | 0.69 | ALDH1A1 (0.54) | — | |
| SCHEMBL8035719 | 0.69 | LTA4H (0.63) | KDM4ECACNA1GSIGMAR1KCNH2 | |
| SCHEMBL8238268 | 0.68 | SLC6A2 (0.40) | KDM4EHTTCACNA1GSIGMAR1KCNH2 | |
| SCHEMBL16226160 | 0.68 | KDM4E (0.72) | KDM4EHTTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1099692-B1 | N,N-SUBSTITUTED CYCLIC AMINE DERIVATIVES | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6737425-B1 | SUCH AS 1-((4-CYANO-5-METHYL-4-PHENYL)HEXYL)-4-(2-(4-FLUORO -PHENOXY)ETHYL)PIPERAZINE; NERVE SELECTIVE CALCIUM ANTAGONISTS | EISAI CO., LTD. (JP) | 2004-05-18 | — | — | US | disclosed |
| EP-1099692-A1 | N,N-SUBSTITUTED CYCLIC AMINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-05-16 | — | — | EP | disclosed |