Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755757 | 0.95 | KDM4E (0.41) | ACACBKDM4EMEN1LMNAHTT | |
| SCHEMBL5759242 | 0.95 | KDM4E (0.41) | ACACBKDM4EMEN1LMNAHTT | |
| SCHEMBL5752573 | 0.95 | KDM4E (0.41) | ACACBKDM4EMEN1LMNAHTT | |
| SCHEMBL5757202 | 0.94 | KDM4E (0.41) | ACACBKDM4EMEN1LMNAHTT | |
| SCHEMBL5752594 | 0.93 | REN (0.40) | ACACBKDM4EMEN1LMNAHTT | |
| SCHEMBL5754926 | 0.91 | ALDH1A1 (0.43) | ACACBKDM4EMEN1LMNAHTT | |
| SCHEMBL5756303 | 0.88 | KMT2A (0.37) | ACACBKDM4EMEN1LMNAHTT | |
| SCHEMBL5753257 | 0.87 | MEN1 (0.43) | MEN1LMNAKMT2AALDH1A1POLB | |
| SCHEMBL5753466 | 0.86 | ALDH1A1 (0.42) | ACACBKDM4EKMT2AALDH1A1POLB | |
| SCHEMBL5757305 | 0.85 | REN (0.41) | MEN1KMT2AALDH1A1PSMB8CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |