Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759242 | 0.95 | KDM4E (0.41) | ALDH1A1GHSRKDM4EMEN1LMNA | |
| SCHEMBL5752573 | 0.95 | KDM4E (0.41) | ALDH1A1GHSRKDM4EMEN1LMNA | |
| SCHEMBL5755757 | 0.95 | KDM4E (0.41) | ALDH1A1GHSRKDM4EMEN1LMNA | |
| SCHEMBL5757202 | 0.94 | KDM4E (0.41) | ALDH1A1GHSRKDM4EMEN1LMNA | |
| SCHEMBL5752594 | 0.91 | REN (0.40) | ALDH1A1KDM4EMEN1LMNAHTT | |
| SCHEMBL5754716 | 0.91 | ACACB (0.39) | ALDH1A1GHSRKDM4EMEN1LMNA | |
| SCHEMBL5756787 | 0.87 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2GHSRMEN1LMNA | |
| SCHEMBL5757162 | 0.87 | CACNA1B (0.34) | ALDH1A1KMT2APOLBCACNA1BP2RX7 | |
| SCHEMBL5756478 | 0.87 | CACNA1B (0.34) | ALDH1A1KMT2APOLBCACNA1BP2RX7 | |
| SCHEMBL5753257 | 0.87 | MEN1 (0.43) | ALDH1A1MEN1LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |