Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751902 | 0.81 | SIGMAR1 (0.42) | CCR1CACNA1GSIGMAR1CCR3MEN1 | |
| SCHEMBL5749643 | 0.66 | POLB (0.46) | CCR1CACNA1GSIGMAR1CCR3MEN1 | |
| SCHEMBL5752126 | 0.65 | SIGMAR1 (0.42) | CCR1CACNA1GSIGMAR1CCR3MEN1 | |
| SCHEMBL5754225 | 0.64 | CCR1 (0.52) | CCR1SIGMAR1MEN1 | |
| SCHEMBL5754449 | 0.64 | SIGMAR1 (0.48) | CCR1CACNA1GSIGMAR1CCR3 | |
| SCHEMBL5752536 | 0.64 | CCR1 (0.41) | CCR1CACNA1GSIGMAR1CCR3MEN1 | |
| SCHEMBL5617444 | 0.63 | HTR7 (0.49) | CACNA1GSIGMAR1 | |
| SCHEMBL5753240 | 0.63 | SIGMAR1 (0.45) | CCR1CACNA1GSIGMAR1CCR3MEN1 | |
| SCHEMBL5617293 | 0.63 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL5617456 | 0.63 | KCNH2 (0.55) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1099692-B1 | N,N-SUBSTITUTED CYCLIC AMINE DERIVATIVES | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |