Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757747 | 0.94 | PHF8 (0.51) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL5758470 | 0.86 | NPC1 (0.53) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL5760700 | 0.85 | PHF8 (0.51) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL5755514 | 0.82 | NPC1 (0.60) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL5756087 | 0.78 | KDM4C (0.47) | PHF8HPGDSCYP2E1CYP3A4CYP2D6 | |
| SCHEMBL7151014 | 0.77 | NPC1 (0.48) | NPC1RAB9ALMNAHTTNR1I3 | |
| SCHEMBL5758218 | 0.76 | KDM5B (0.48) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL5758123 | 0.75 | KDM5B (0.50) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL5759382 | 0.75 | HPGDS (0.59) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL5754960 | 0.75 | P2RX7 (0.42) | NPC1RAB9AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194144-B1 | ANTIBACTERIAL COMPOUNDS | AFFINIUM PHARM INC (CA) | 2006-11-02 | — | — | EP | claimed |
| US-20030149089-A1 | Antibacterial compounds | SMITHKLINE BEECHAM CORPORATION | 2003-08-07 | — | — | US | claimed |
| EP-1194144-B1 | ANTIBACTERIAL COMPOUNDS | AFFINIUM PHARM INC (CA) | 2006-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149089-A1 | Antibacterial compounds | MRPL21, MRPS28, SPOUT1 | NPC1 103/4885RAB9A 140/4885ALDH1A1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.