Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 3/20 | 0.34 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758199 | 0.91 | CACNA1B (0.43) | CACNA1BHSD17B10ATMYAP1GHSR | |
| SCHEMBL5754912 | 0.88 | CACNA1B (0.43) | CACNA1BHSD17B10ATMYAP1MEN1 | |
| SCHEMBL5758645 | 0.88 | CACNA1B (0.43) | CACNA1BHSD17B10ATMYAP1MEN1 | |
| SCHEMBL5754050 | 0.87 | NPC1 (0.37) | CACNA1BNPC1RAB9APKMCTSD | |
| SCHEMBL5759035 | 0.86 | CACNA1B (0.49) | CACNA1BHSD17B10ATMYAP1GHSR | |
| SCHEMBL5754736 | 0.85 | CACNA1B (0.40) | CACNA1BHSD17B10ATMMEN1KMT2A | |
| SCHEMBL5753816 | 0.85 | NPC1 (0.37) | NPC1RAB9APKMCTSDMEN1 | |
| SCHEMBL5756658 | 0.84 | CACNA1B (0.39) | CACNA1BHSD17B10ATMMEN1KMT2A | |
| SCHEMBL5757036 | 0.83 | CACNA1B (0.45) | CACNA1BHSD17B10KMT2A | |
| SCHEMBL5755981 | 0.82 | KMT2A (0.38) | CACNA1BHSD17B10YAP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |