Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757158 | 0.85 | HSD11B1 (0.54) | HSD11B1CYP1A2CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL9377800 | 0.84 | HSD11B1 (0.57) | HSD11B1CYP1A2CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL5758045 | 0.80 | HTR2A (0.44) | CYP2C19HSD11B1CYP1A2CYP2C9 | |
| SCHEMBL5754847 | 0.80 | EPHX2 (0.53) | CYP2C19CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL5756941 | 0.79 | GAA (0.46) | CYP2C19HSD11B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5760413 | 0.76 | HTR2A (0.58) | CYP1A2CYP3A4CYP2D6SMN1; SMN2LMNA | |
| SCHEMBL5757058 | 0.76 | SLC18A3 (0.47) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5755104 | 0.76 | HTR2A (0.47) | CYP2C19HSD11B1CYP1A2CYP2C9 | |
| SCHEMBL7247259 | 0.75 | HSD11B1 (0.52) | HSD11B1CYP1A2CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL1582935 | 0.73 | LMNA (0.54) | CYP2C19HSD11B1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | claimed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | claimed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | claimed |
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |