Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ATP4A | P20648 | 1/20 | 0.48 |
| ▸ | ATP4B | P51164 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763074 | 0.85 | FFAR1 (0.60) | FFAR1RAB9ANPC1MAPK1TDP1 | |
| SCHEMBL5760515 | 0.82 | FFAR1 (0.59) | FFAR1RAB9ANPC1MAPK1TDP1 | |
| SCHEMBL5759785 | 0.80 | HMOX1 (0.85) | HMOX1TBXAS1 | |
| SCHEMBL5758141 | 0.78 | HMOX1 (0.52) | TDP1L3MBTL1HMOX1ATP4AATP4B | |
| SCHEMBL3504984 | 0.78 | TLR9 (0.61) | RAB9ANPC1SMN1; SMN2ATP4AATP4B | |
| SCHEMBL5760668 | 0.78 | FFAR1 (0.59) | FFAR1TDP1L3MBTL1HMOX1ATP4A | |
| SCHEMBL5762895 | 0.78 | ATP4A (0.56) | HMOX1ATP4AATP4B | |
| SCHEMBL5757778 | 0.77 | HMOX1 (0.83) | HMOX1TBXAS1 | |
| SCHEMBL5759390 | 0.77 | ATP4A (0.66) | HMOX1ATP4AATP4B | |
| SCHEMBL3504601 | 0.76 | QPCT (0.55) | LMNATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |