Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5760515 | 0.97 | FFAR1 (0.59) | FFAR1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL5756965 | 0.85 | FFAR1 (0.59) | FFAR1RAB9ANPC1SMN1; SMN2TDP1 | |
| SCHEMBL5761248 | 0.83 | HMOX1 (0.47) | FFAR1HMOX1CYP19A1TBXAS1 | |
| SCHEMBL5759372 | 0.82 | HMOX1 (0.48) | FFAR1RAB9ANPC1LMNAHMOX1 | |
| SCHEMBL5761892 | 0.80 | HMOX1 (0.47) | FFAR1LMNAMAPK1HSD17B10HMOX1 | |
| SCHEMBL5761441 | 0.80 | HMOX1 (0.47) | RAB9ANPC1LMNAHMOX1NFKB1 | |
| SCHEMBL5759023 | 0.79 | ATP4A (0.50) | LMNAHMOX1KDM4ECYP19A1 | |
| SCHEMBL5762941 | 0.79 | HMOX1 (0.49) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL5761627 | 0.79 | HMOX1 (0.51) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL5759340 | 0.78 | PPARA (0.52) | FFAR1MAPK1HSD17B10HMOX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |