Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.51 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5754840 | 0.98 | POLB (0.58) | POLBSMN1; SMN2SIGMAR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6007900 | 0.97 | POLB (0.55) | POLBSMN1; SMN2SIGMAR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL5757770 | 0.80 | SLC6A4 (0.58) | POLBSMN1; SMN2SIGMAR1DPP4DPP7 | |
| SCHEMBL16595691 | 0.79 | CSNK2A1 (0.53) | CYP1A2CYP2D6 | |
| SCHEMBL21729367 | 0.78 | SLC6A4 (0.55) | DPP7CYP2D6 | |
| SCHEMBL6009428 | 0.78 | ALDH1A1 (0.53) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL5761056 | 0.78 | PNMT (0.53) | SIGMAR1PNMTDPP4DPP7CYP3A4 | |
| Hydrochloric Acid SCHEMBL6007421 | 0.77 | ALDH1A1 (0.52) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1755597 | 0.77 | ALOX15 (0.47) | POLBCYP1A2CYP2D6TP53CYP3A4 | |
| SCHEMBL21729327 | 0.77 | SLC6A4 (0.56) | DPP7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |