Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595036 | 0.92 | ADRA1D (0.44) | ADRA1DCYP4F2CYP4A11PTGDR2CCR2 | |
| SCHEMBL6196958 | 0.92 | ADRA1D (0.47) | ADRA1DPTGDR2PTGES2CCR2NPC1 | |
| SCHEMBL1013697 | 0.92 | ADRA1D (0.44) | ADRA1DCYP4F2CYP4A11PTGDR2CCR2 | |
| SCHEMBL5756525 | 0.83 | CA2 (0.37) | PTGES2RAB9AL3MBTL1PTGS2PIK3CD | |
| SCHEMBL5760478 | 0.81 | ADRA1D (0.40) | ADRA1DPTGDR2PTGES2CCR2NPC1 | |
| SCHEMBL27624382 | 0.79 | ADRA1D (0.42) | ADRA1DPTGDR2PTGES2CCR2L3MBTL1 | |
| SCHEMBL1013610 | 0.78 | GSTO1 (0.44) | PTGES2CCR2SMN1; SMN2L3MBTL1PTGS2 | |
| SCHEMBL1015882 | 0.78 | GSTO1 (0.44) | CYP4F2CYP4A11CCR2HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27763840 | 0.77 | CYP4F2 (0.40) | ADRA1DCYP4F2CYP4A11PTGES2HPGD | |
| SCHEMBL13211313 | 0.76 | ADRA1D (0.45) | ADRA1DPTGDR2CCR2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611088-A2 | HYDROXAMATES AS THERAPEUTIC AGENTS | AXYS PHARMACEUTICALS, INC. (US) | 2006-01-04 | — | — | EP | claimed |
| WO-2004092115-A2 | HYDROXAMATES AS THERAPEUTIC AGENTS | AXYS PHARMACEUTICALS INC. (US) | 2004-10-28 | — | — | WO | claimed |