Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752463 | 0.88 | GRM5 (0.53) | GRM5KCNH2 | |
| SCHEMBL2893476 | 0.83 | GRM5 (0.37) | GRM5KCNH2 | |
| SCHEMBL2893053 | 0.83 | GRM5 (0.44) | GRM5KCNH2 | |
| SCHEMBL2889410 | 0.80 | RXRA (0.36) | — | |
| SCHEMBL2893046 | 0.79 | GRM5 (0.35) | GRM5 | |
| SCHEMBL2893434 | 0.79 | GRM5 (0.53) | GRM5KCNH2 | |
| SCHEMBL2895459 | 0.78 | GRM5 (0.57) | GRM5KCNH2 | |
| SCHEMBL2895374 | 0.78 | GRM5 (0.49) | GRM5KCNH2 | |
| SCHEMBL2897330 | 0.78 | MAPT (0.39) | KCNH2 | |
| SCHEMBL2895669 | 0.78 | ALDH1A1 (0.38) | GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716125-A1 | TETRAZOLE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONITS | AstraZeneca AB (SE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005080356-A1 | TETRAZOLE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONITS | ASTRAZENECA AB (SE) | 2005-09-01 | — | — | WO | disclosed |