Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756078 | 0.85 | KDM4E (0.55) | CA2KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL5761063 | 0.78 | NPC1 (0.53) | RAB9ANPC1APPSULT1A1SMN1; SMN2 | |
| SCHEMBL5755215 | 0.76 | MAPK1 (0.52) | KMT2ARAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL5758909 | 0.72 | ILK (0.55) | APPGAA | |
| SCHEMBL5760456 | 0.72 | MAPT (0.48) | CA2KMT2ARAB9ANPC1APP | |
| SCHEMBL686543 | 0.71 | ILK (0.73) | — | |
| SCHEMBL17801689 | 0.70 | NPC1 (0.56) | KMT2ARAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL11024521 | 0.69 | KMT2A (0.57) | CA2KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5756650 | 0.68 | CA2 (0.60) | CA2KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL12095376 | 0.68 | SMN1; SMN2 (0.67) | KMT2ARAB9AMEN1NPC1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539723-B1 | NOVEL USE OF BENZOTHIAZOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2006-05-24 | — | — | EP | claimed |