Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858333 | 0.80 | GOT1 (0.50) | GOT1JAK2P2RX7TYK2CYP2C19 | |
| SCHEMBL8170897 | 0.80 | GOT1 (0.55) | GOT1ALDH1A1MAP4K4CLK4ROCK2 | |
| SCHEMBL5940546 | 0.80 | GOT1 (0.50) | GOT1KDM4EALDH1A1PIM1P2RX7 | |
| SCHEMBL10858944 | 0.80 | GOT1 (0.50) | GOT1P2RX7CYP2C19 | |
| SCHEMBL5756006 | 0.78 | IL1B (0.53) | KDM4EALDH1A1POLBGAAMAPK1 | |
| SCHEMBL11324922 | 0.77 | GOT1 (0.52) | GOT1ALDH1A1STK17AP2RX7KARS1 | |
| SCHEMBL13356938 | 0.77 | TLR8 (0.47) | GOT1KDM4EALDH1A1MAPK1MAP4K4 | |
| Hydrochloric Acid SCHEMBL5756281 | 0.76 | IL1B (0.51) | KDM4EALDH1A1POLBGAAMAPK1 | |
| SCHEMBL4099219 | 0.76 | KDM4E (0.40) | KDM4EALDH1A1POLBGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL8048735 | 0.76 | GOT1 (0.50) | GOT1ALDH1A1STK17AP2RX7KARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266651-B1 | UV absorbing and photostabilizing agents and compositions and external preparation for skin | SHISEIDO CO LTD (JP) | 2006-09-06 | — | — | EP | disclosed |
| US-4569934-A | ANTIANXIETY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-02-11 | — | — | US | disclosed |