Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637979 | 0.84 | ALDH1A1 (0.40) | TSHRHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5756144 | 0.80 | CSNK2A1 (0.41) | HTR2AHTR2CTSHRHTR2BCSNK2A1 | |
| SCHEMBL11890403 | 0.78 | CSNK2A1 (0.43) | HTR2AHTR2CTSHRHTR2BCSNK2A1 | |
| SCHEMBL6445833 | 0.77 | EPAS1 (0.34) | HTR2AHTR2CFFAR4MAP2 | |
| SCHEMBL6446720 | 0.75 | CYP3A4 (0.39) | HTR2AHTR2CTSHRHTR2BCYP3A4 | |
| SCHEMBL16953753 | 0.75 | CSNK2A1 (0.41) | HTR2AHTR2CTSHRHTR2BCSNK2A1 | |
| SCHEMBL2311541 | 0.74 | TDP1 (0.41) | TSHRCYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL16959273 | 0.74 | CSNK2A1 (0.38) | HTR2AHTR2CTSHRHTR2BCSNK2A1 | |
| SCHEMBL30933788 | 0.73 | ERN1 (0.47) | HTR2AHTR2CTSHRHTR2BCSNK2A1 | |
| SCHEMBL4209586 | 0.73 | ERN1 (0.47) | HTR2AHTR2CTSHRHTR2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658273-A1 | COMPOUNDS, METHODS AND FORMULATIONS FOR THE ORAL DELIVERY OF A GLUCAGON LIKE PEPTIDE (GLP)-1 COMPOUND OR AN MELANOCORTIN 4 RECEPTOR (MC4) AGONIST PEPTIDE | ELI LILLY AND COMPANY (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005019184-A1 | COMPOUNDS, METHODS AND FORMULATIONS FOR THE ORAL DELIVERY OF A GLUCAGON LIKE PEPTIDE (GLP)-1 COMPOUND OR AN MELANOCORTIN 4 RECEPTOR (MC4) AGONIST PEPTIDE | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |