SCHEMBL5758271

SCHEMBL5758271

CS(=O)(=O)NCCC(c1ccccc1)N1CCC(Cc2ccccc2)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 1/20 0.52
ALDH1A1 P00352 1/20 0.46
SLC6A2 P23975 3/20 0.46
SLC6A3 Q01959 3/20 0.46
CARM1 Q86X55 1/20 0.44
PRMT6 Q96LA8 1/20 0.44
GRIN2B Q13224 6/20 0.44
ADRA2A P08913 5/20 0.44
HTR2A P28223 5/20 0.44
ADRA1A P35348 5/20 0.44
GRIN1 Q05586 4/20 0.44
HTR2B P41595 4/20 0.44
SIGMAR1 Q99720 3/20 0.44
GRIN2D O15399 2/20 0.44
HTR1A P08908 2/20 0.44
GRIN2A Q12879 2/20 0.44
GRIN2C Q14957 2/20 0.44
LMNA P02545 1/20 0.44
ADRB1 P08588 1/20 0.44
DRD2 P14416 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5755953 0.87 CCR5 (0.49) CCR5ALDH1A1SLC6A2SLC6A3LMNA
SCHEMBL5757613 0.85 MEN1 (0.51) CCR5ALDH1A1LMNAOPRK1CYP1A2
SCHEMBL5757908 0.84 CARM1 (0.59) SLC6A2SLC6A3CARM1PRMT6GRIN2B
SCHEMBL5758217 0.82 ALDH1A1 (0.56) CCR5ALDH1A1CYP2D6TSHR
SCHEMBL5759449 0.82 CCR5 (0.44) CCR5SLC6A2SLC6A3GRIN2BADRA2A
SCHEMBL5757825 0.81 SLC6A2 (0.54) CCR5SLC6A2SLC6A3GRIN2BGRIN1
SCHEMBL5755428 0.81 SLC6A2 (0.47) CCR5SLC6A2SLC6A3CARM1PRMT6
SCHEMBL5754014 0.80 CYP19A1 (0.48) CCR5ALDH1A1LMNADRD2ADRA2C
SCHEMBL7405479 0.80 OPRK1 (0.52) CCR5SLC6A2SLC6A3GRIN2BADRA2A
SCHEMBL5758650 0.78 CCR3 (0.60) SLC6A2SLC6A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401821-A4 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK CORP (KR) 2006-05-31 EP claimed
EP-1401821-A1 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK Corporation (KR) 2004-03-31 EP claimed
WO-2002100848-A1 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK CORPORATION (KR) 2002-12-19 WO claimed
EP-1401821-A4 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK CORP (KR) 2006-05-31 EP disclosed
EP-1401821-A1 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK Corporation (KR) 2004-03-31 EP disclosed
WO-2002100848-A1 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK CORPORATION (KR) 2002-12-19 WO disclosed