Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 1.00 |
| ▸ | PRKCA | P17252 | 14/20 | 1.00 |
| ▸ | PRKCB | P05771 | 13/20 | 1.00 |
| ▸ | PRKCG | P05129 | 11/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 9/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.70 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.70 |
| ▸ | PRKACA | P17612 | 3/20 | 0.54 |
| ▸ | PRKACG | P22612 | 3/20 | 0.54 |
| ▸ | PRKACB | P22694 | 3/20 | 0.54 |
| ▸ | PIM1 | P11309 | 2/20 | 0.54 |
| ▸ | PRKCH | P24723 | 3/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.50 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.50 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771589 | 0.92 | PRKCA (0.84) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL5758532 | 0.92 | PRKCA (0.84) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL5755677 | 0.89 | PRKCA (0.80) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL3783864 | 0.89 | PRKCA (0.80) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL3775416 | 0.88 | GSK3B (0.79) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL3784374 | 0.86 | PRKCA (0.76) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL5814373 | 0.86 | PRKCA (1.00) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL5754176 | 0.85 | PRKCA (0.75) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL3773391 | 0.84 | PRKCA (0.73) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL5756314 | 0.83 | PRKCA (0.73) | GSK3BPRKCAPRKCBPRKCGPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362047-B1 | INDAZOLYL-SUBSTITUTED PYRROLINE COMPOUNDS AS KINASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2006-05-17 | — | — | EP | disclosed |