Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 6/20 | 0.41 |
| ▸ | ATRIP | Q8WXE1 | 6/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30014876 | 0.98 | PIK3CD (0.50) | PIK3CDPIK3CAPIK3CBMAPTLMNA | |
| SCHEMBL5755960 | 0.82 | POLB (0.56) | MAPTROCK2ROCK1CDC42BPBATR | |
| Hydrochloric Acid SCHEMBL29878858 | 0.81 | POLB (0.54) | MAPTROCK2ROCK1CDC42BPBATR | |
| SCHEMBL5758664 | 0.81 | NCF1 (0.45) | TIPARPROCK2ROCK1CDC42BPB | |
| Hydrochloric Acid SCHEMBL4810850 | 0.79 | NCF1 (0.44) | LMNATIPARPROCK2ROCK1CDC42BPB | |
| SCHEMBL541490 | 0.75 | POLB (0.49) | PIK3CDPIK3CAPIK3CBMAPTLMNA | |
| SCHEMBL5611260 | 0.74 | ATR (0.48) | PIK3CDPIK3CAPIK3CBLMNAATR | |
| SCHEMBL10664047 | 0.71 | JAK2 (0.47) | PIK3CDPIK3CAPIK3CBMAPTTIPARP | |
| SCHEMBL4032846 | 0.70 | MAPT (0.47) | MAPTLMNAMEN1NPC1RAB9A | |
| SCHEMBL31244640 | 0.70 | TIPARP (0.71) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077310-B1 | SIGMA-1 RECEPTOR LIGANDS AND USES THEREOF | UNIV STRASBOURG (FR) | 2024-05-01 | — | — | EP | claimed |
| EP-1266651-B1 | UV absorbing and photostabilizing agents and compositions and external preparation for skin | SHISEIDO CO LTD (JP) | 2006-09-06 | — | — | EP | disclosed |