Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.47 |
| ▸ | CDC42BPB | Q9Y5S2 | 6/20 | 0.47 |
| ▸ | CDC42BPA | Q5VT25 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 2/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29878858 | 0.98 | POLB (0.54) | POLBALDH1A1ROCK2ROCK1CDC42BPB | |
| SCHEMBL5758664 | 0.84 | NCF1 (0.45) | ROCK2ROCK1CDC42BPB | |
| SCHEMBL5758663 | 0.82 | PIK3CD (0.51) | POLBROCK2ROCK1CDC42BPBMAPT | |
| Hydrochloric Acid SCHEMBL4810850 | 0.82 | NCF1 (0.44) | ALDH1A1ROCK2ROCK1CDC42BPB | |
| Hydrochloric Acid SCHEMBL30014876 | 0.81 | PIK3CD (0.50) | POLBROCK2ROCK1CDC42BPBMAPT | |
| SCHEMBL30876044 | 0.73 | NUDT1 (0.51) | ALDH1A1MAPTATRATRIP | |
| SCHEMBL31145125 | 0.72 | TSHR (0.42) | POLBALDH1A1ROCK2ROCK1CDC42BPB | |
| SCHEMBL20832011 | 0.71 | TRPC5 (0.69) | KMT2ATRPC5 | |
| Hydrochloric Acid SCHEMBL30872395 | 0.71 | USP2 (0.41) | POLBALDH1A1ROCK2ROCK1CDC42BPB | |
| SCHEMBL28044373 | 0.70 | CHKA (0.41) | POLBALDH1A1ROCK2ROCK1CDC42BPB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077310-A1 | SIGMA-1 RECEPTOR LIGANDS AND USES THEREOF | Université de Strasbourg (FR) | 2022-10-26 | — | — | EP | disclosed |
| EP-1266651-B1 | UV absorbing and photostabilizing agents and compositions and external preparation for skin | SHISEIDO CO LTD (JP) | 2006-09-06 | — | — | EP | disclosed |