Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 8/20 | 0.55 |
| ▸ | ATP4B | P51164 | 8/20 | 0.55 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759407 | 1.00 | ATP4A (0.55) | ATP4AATP4BHMOX1LTA4HQPCT | |
| SCHEMBL5755640 | 0.83 | ERBB2 (0.54) | ATP4AATP4BHMOX1LTA4HKMT2A | |
| SCHEMBL5755643 | 0.83 | ERBB2 (0.54) | ATP4AATP4BHMOX1LTA4HKMT2A | |
| SCHEMBL5760882 | 0.80 | ERBB2 (0.57) | ATP4AATP4BHMOX1 | |
| SCHEMBL5760885 | 0.80 | ERBB2 (0.57) | ATP4AATP4BHMOX1 | |
| SCHEMBL5758829 | 0.79 | ERBB2 (0.57) | ATP4AATP4BHMOX1 | |
| SCHEMBL5758825 | 0.79 | ERBB2 (0.57) | ATP4AATP4BHMOX1 | |
| SCHEMBL5761163 | 0.79 | ERBB2 (0.57) | ATP4AATP4BHMOX1 | |
| SCHEMBL5761155 | 0.79 | ERBB2 (0.57) | ATP4AATP4BHMOX1 | |
| SCHEMBL5760119 | 0.78 | HMOX1 (0.47) | HMOX1QPCTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |