Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759340 | 0.83 | PPARA (0.52) | HMOX1HSD17B10FFAR1PPARGQPCT | |
| SCHEMBL5761373 | 0.82 | HMOX1 (0.49) | HMOX1ALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL5760940 | 0.80 | PPARA (0.51) | HMOX1HSD17B10FFAR1PPARGQPCT | |
| SCHEMBL5760105 | 0.80 | CYP11B1 (0.46) | HMOX1ALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL6960613 | 0.79 | FFAR1 (0.48) | ALDH1A1GAAHSD17B10HPGDFFAR1 | |
| SCHEMBL5759405 | 0.78 | ATP4A (0.55) | HMOX1QPCTKMT2A | |
| SCHEMBL5759407 | 0.78 | ATP4A (0.55) | HMOX1QPCTKMT2A | |
| SCHEMBL4034983 | 0.77 | KDR (0.53) | ALDH1A1GAAHSD17B10HPGDFFAR1 | |
| SCHEMBL4033057 | 0.77 | FFAR1 (0.48) | ALDH1A1GAAHSD17B10HPGDFFAR1 | |
| SCHEMBL6963929 | 0.76 | PPARG (0.46) | ALDH1A1GAAHSD17B10HPGDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |