Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757198 | 0.87 | MMP1 (0.70) | MMP1ADAM17 | |
| SCHEMBL5760551 | 0.84 | MMP1 (0.75) | MMP1ADAM17 | |
| SCHEMBL5756496 | 0.82 | MMP1 (0.75) | MMP1ADAM17 | |
| SCHEMBL5761544 | 0.81 | MMP1 (0.56) | MMP1ADAM17 | |
| SCHEMBL5761953 | 0.80 | MMP1 (0.41) | MMP1ADAM17 | |
| SCHEMBL5757615 | 0.79 | MMP1 (0.54) | MMP1ADAM17 | |
| SCHEMBL7150947 | 0.77 | ADAM17 (0.49) | MMP1ADAM17 | |
| SCHEMBL7150958 | 0.77 | ADAM17 (0.49) | MMP1ADAM17 | |
| SCHEMBL5761741 | 0.77 | ADAM17 (0.49) | MMP1ADAM17 | |
| SCHEMBL7150952 | 0.77 | ADAM17 (0.49) | MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104403-B1 | HYDROXY PIPECOLATE HYDROXAMIC ACID DERIVATIVES AS MMP INHIBITORS | PFIZER PROD INC (US) | 2006-05-10 | — | — | EP | claimed |