Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 17/20 | 0.71 |
| ▸ | PRKCB | P05771 | 14/20 | 0.71 |
| ▸ | PRKCG | P05129 | 13/20 | 0.71 |
| ▸ | PRKCA | P17252 | 13/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.71 |
| ▸ | PRKCD | Q05655 | 7/20 | 0.71 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.71 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.45 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774167 | 0.86 | GSK3B (0.81) | GSK3BPRKCBPRKCGPRKCAKCNH2 | |
| SCHEMBL5754534 | 0.85 | GSK3B (0.76) | GSK3BPRKCBPRKCGPRKCAKCNH2 | |
| SCHEMBL5756379 | 0.85 | GSK3B (0.81) | GSK3BPRKCBPRKCGPRKCAKCNH2 | |
| SCHEMBL5757856 | 0.83 | GSK3B (1.00) | GSK3BPRKCBPRKCGPRKCAKCNH2 | |
| SCHEMBL5757333 | 0.81 | GSK3B (0.85) | GSK3BPRKCBPRKCGPRKCAKCNH2 | |
| SCHEMBL6069263 | 0.77 | GSK3B (0.61) | GSK3BPRKCBPRKCGPRKCAKCNH2 | |
| SCHEMBL5755363 | 0.76 | GSK3B (0.77) | GSK3BPRKCBPRKCGPRKCAKCNH2 | |
| SCHEMBL5754543 | 0.76 | PRKCB (0.65) | GSK3BPRKCBPRKCGPRKCAKCNH2 | |
| SCHEMBL3774788 | 0.75 | GSK3B (0.80) | GSK3BPRKCBPRKCGPRKCAKCNH2 | |
| SCHEMBL5757178 | 0.74 | GSK3B (0.79) | GSK3BPRKCBPRKCGPRKCAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362047-B1 | INDAZOLYL-SUBSTITUTED PYRROLINE COMPOUNDS AS KINASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2006-05-17 | — | — | EP | disclosed |