Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20384257 | 0.85 | CYP1A2 (0.36) | — | |
| SCHEMBL5762684 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL17927261 | 0.79 | KDM1A (0.35) | KDM1ARCOR1KCNH2KDM1B | |
| SCHEMBL20226666 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL27305620 | 0.77 | NOTUM (0.35) | — | |
| SCHEMBL19931236 | 0.76 | EPAS1 (0.49) | — | |
| SCHEMBL20308686 | 0.75 | KIF11 (0.41) | KDM1A | |
| SCHEMBL19450815 | 0.75 | KDM1A (0.35) | KDM1AKCNH2KDM1B | |
| SCHEMBL2653697 | 0.74 | TSHR (0.39) | — | |
| SCHEMBL19931120 | 0.71 | ALDH1A1 (0.42) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611091-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004089885-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | disclosed |