Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 3/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.40 |
| ▸ | ATP4B | P51164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759372 | 0.97 | HMOX1 (0.48) | HMOX1CYP11B1CYP11B2KDM4ELMNA | |
| SCHEMBL5760515 | 0.83 | FFAR1 (0.59) | HMOX1KDM4ELMNANPC1NFKB1 | |
| SCHEMBL5760827 | 0.82 | HMOX1 (0.48) | HMOX1CYP11B1CYP11B2KDM4ELMNA | |
| SCHEMBL5763074 | 0.80 | FFAR1 (0.60) | HMOX1KDM4ELMNANPC1NFKB1 | |
| SCHEMBL5761248 | 0.80 | HMOX1 (0.47) | HMOX1CYP11B1CYP11B2ATP4AATP4B | |
| SCHEMBL5760940 | 0.79 | PPARA (0.51) | HMOX1CYP11B1CYP11B2KDM4ELMNA | |
| SCHEMBL5762941 | 0.79 | HMOX1 (0.49) | HMOX1CYP11B1CYP11B2ATP4AATP4B | |
| SCHEMBL5761627 | 0.79 | HMOX1 (0.51) | HMOX1CYP11B1CYP11B2NOS1 | |
| SCHEMBL5761819 | 0.79 | HMOX1 (0.47) | HMOX1KDM4ELMNANOS1ATP4A | |
| SCHEMBL5762174 | 0.79 | ATP4A (0.52) | HMOX1KDM4ELMNANOS1ATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |