SCHEMBL57616

SCHEMBL57616

O=[N+]([O-])c1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.56
TSHR P16473 3/20 0.56
TDP1 Q9NUW8 2/20 0.55
ALDH1A1 P00352 4/20 0.53
MEN1 O00255 6/20 0.53
KMT2A Q03164 6/20 0.53
MAPT P10636 5/20 0.53
RAB9A P51151 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALPG P10696 1/20 0.53
NPC1 O15118 3/20 0.51
MAOA P21397 1/20 0.51
MAOB P27338 1/20 0.51
PTPRC P08575 2/20 0.50
CYP19A1 P11511 2/20 0.50
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
CES1 P23141 1/20 0.50
S100A4 P26447 1/20 0.50
ATM Q13315 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29929890 1.00 LMNA (0.56) LMNATSHRTDP1ALDH1A1MEN1
Methyl Alcohol SCHEMBL28005405 0.94 MEN1 (0.52) LMNATSHRTDP1ALDH1A1MEN1
SCHEMBL5167846 0.93 LMNA (0.54) LMNATSHRTDP1ALDH1A1MEN1
SCHEMBL2760792 0.93 LMNA (0.54) LMNATSHRTDP1ALDH1A1MEN1
SCHEMBL31677837 0.93 LMNA (0.54) LMNATSHRTDP1ALDH1A1MEN1
SCHEMBL28122579 0.91 TSHR (0.59) LMNATSHRTDP1ALDH1A1MAPT
SCHEMBL28688755 0.90 TSHR (0.47) LMNATSHRTDP1ALDH1A1MEN1
SCHEMBL3829978 0.88 TSHR (0.56) LMNATSHRTDP1ALDH1A1MAPT
SCHEMBL28338203 0.86 TSHR (0.54) LMNATSHRTDP1ALDH1A1MAPT
SCHEMBL28158961 0.84 ALDH1A1 (0.71) LMNATSHRTDP1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108624-A Preparation method and application of high-orientation liquid crystal polymer and liquid crystal elastomer 烟台先进材料与绿色制造山东省实验室 2024-05-31 CN claimed
CN-114507252-B Novel method for synthesizing arylsilane compound 广西大学 2023-10-27 CN claimed
CN-107540555-B A method of nitro hydrogenation being reduced to amino in supergravity reactor 北京化工大学 2019-07-12 CN claimed
CN-105899578-B Aromatics dispersant composition 路博润先进材料公司 2019-01-04 CN claimed
US-10043978-B2 Organic semiconductor formulations FLEXTERRA, INC. (US) 2018-08-07 US claimed
CN-107540555-A A kind of method that nitro hydrogenation is reduced to amino in supergravity reactor 北京化工大学 2018-01-05 CN claimed
CN-106977406-A The method of continuous autoclave catalytic hydrogenation synthesizing amino naphthalene 江苏华达化工集团有限公司 2017-07-25 CN claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-105899578-A Aromatic dispersant composition 路博润先进材料公司 2016-08-24 CN claimed
CN-102850225-B Method for synthesizing alpha-nitronaphthalene and beta-nitronaphthalene ANHUI HUAIHUA CHEMICAL GROUP 2014-07-16 CN claimed
EP-0352563-B1 Process for the hydroxylation of electrophilic aromatic compounds BAYER AG (DE) 1994-01-19 EP claimed
EP-0543307-A2 Nootropic agent SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1993-05-26 EP claimed
US-4962198-A Process for the hydroxylation of electrophilic aromatic compounds BAYER AKTIENGESELLSCHAFT (DE) 1990-10-09 US claimed
EP-0352563-A2 Process for the hydroxylation of electrophilic aromatic compounds BAYER AG (DE) 1990-01-31 EP claimed
EP-0174563-B1 PROCESS FOR PREPARING 1-NAPHTHYL AMINE BAYER AG (DE) 1987-11-25 EP claimed
EP-0174563-A1 Process for preparing 1-naphthyl amine BAYER AG (DE) 1986-03-19 EP claimed
US-4294908-A Photoresist composition containing modified cyclized diene polymers JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-10-13 US claimed
EP-0014366-B1 PROCESS FOR THE PREPARATION OF THE MAGNESIUM SALT OF 2-NITRONAPHTHALENE-4,8-DISULPHONIC ACID BAYER AG (DE) 1981-09-16 EP claimed
US-4207266-A CARBON TETRALIDE, HYDROGEN FLUORIDE, LEWIS ACID AD AROMATIC HYDROCARBON ROHM AND HAAS COMPANY (US) 1980-06-10 US claimed
US-4124768-A Process for preparing pure substituted 2,5-diarylamino-terephthalates and the corresponding free acids HOECHST AKTIENGESELLSCHAFT 1978-11-07 US claimed