Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366597 | 0.80 | MAPK1 (0.48) | MTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL14387815 | 0.77 | MTNR1A (0.39) | MTNR1AMTNR1BDYRK1AMAPT | |
| SCHEMBL5378208 | 0.73 | CXCL8 (0.44) | MTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL14387883 | 0.71 | MAPK1 (0.48) | MAPTALDH1A1 | |
| SCHEMBL5362129 | 0.71 | CXCL8 (0.39) | MTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL14356225 | 0.69 | MAPK1 (0.39) | DYRK1AMAPTALDH1A1 | |
| SCHEMBL21315649 | 0.69 | MTNR1A (0.77) | MTNR1AMTNR1BDYRK1A | |
| SCHEMBL29961848 | 0.69 | MTNR1A (0.77) | MTNR1AMTNR1BDYRK1A | |
| SCHEMBL14112985 | 0.69 | PDE3B (0.46) | MTNR1AMTNR1BMAPTALDH1A1PPARG | |
| SCHEMBL9148447 | 0.68 | ALDH1A1 (0.43) | MTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556371-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR | WINSTON PHARMACEUTICALS LLC (US) | 2006-04-19 | — | — | EP | disclosed |