Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 6/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764248 | 0.84 | VNN1 (0.53) | VNN1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1753567 | 0.80 | PTGDR2 (0.67) | VNN1MAPTPLA2G1BHTTATG4B | |
| SCHEMBL20185761 | 0.69 | VNN1 (1.00) | VNN1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL22191031 | 0.68 | RECQL (0.46) | VNN1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL22191191 | 0.67 | VNN1 (0.59) | VNN1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29954826 | 0.66 | VNN1 (0.58) | VNN1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL23405896 | 0.66 | FABP1 (0.54) | VNN1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL22191269 | 0.66 | HDAC3 (0.63) | VNN1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29743851 | 0.66 | FABP1 (0.54) | VNN1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1394190 | 0.66 | HPGDS (0.62) | VNN1HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611091-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2006-01-04 | — | — | EP | claimed |
| WO-2004089885-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | claimed |