Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737794 | 0.70 | KDM4E (0.43) | ALDH1A1MEN1POLBKMT2ATDP1 | |
| SCHEMBL14123168 | 0.62 | NPSR1 (0.47) | ALDH1A1GAAMEN1POLBKMT2A | |
| SCHEMBL5764595 | 0.59 | DGAT1 (0.30) | — | |
| SCHEMBL1018739 | 0.59 | — | — | |
| SCHEMBL5764671 | 0.58 | — | — | |
| SCHEMBL9872008 | 0.56 | KDM4E (0.61) | ALDH1A1GAAMEN1POLBKMT2A | |
| SCHEMBL7226727 | 0.56 | — | — | |
| SCHEMBL5763401 | 0.56 | GAA (0.36) | GAA | |
| SCHEMBL8611287 | 0.54 | — | — | |
| SCHEMBL14780191 | 0.54 | MAOA (0.41) | GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091738-B1 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2006-12-06 | — | — | EP | disclosed |
| EP-1091738-A4 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6384041-B1 | ANTIINFLAMMATORY AGENT, TREATMENT OF SHOCK AND ENZYME INHIBITORS | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |
| EP-1091738-A1 | BICYCLIC sPLA 2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000201-A1 | BICYCLIC sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |