Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.47 |
| ▸ | PDE2A | O00408 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764733 | 0.92 | KDR (0.45) | FGFR1SRCMCHR1TLR7HRH3 | |
| SCHEMBL5767666 | 0.91 | CHKA (0.41) | FGFR1SRCMCHR1TLR7HRH3 | |
| SCHEMBL5767801 | 0.89 | NTRK1 (0.44) | FGFR1SRCTLR7MAOAATM | |
| SCHEMBL5766984 | 0.87 | NTRK1 (0.38) | FGFR1SRCKDR | |
| SCHEMBL5765955 | 0.87 | LTA4H (0.36) | FGFR1SRCKDR | |
| SCHEMBL5765675 | 0.87 | NTRK1 (0.38) | FGFR1SRCKDR | |
| SCHEMBL5764600 | 0.86 | JAK2 (0.47) | FGFR1SRCPDE2ADDB1CRBN | |
| SCHEMBL5768958 | 0.85 | LTA4H (0.39) | FGFR1PDE2AMCHR1HRH3KDR | |
| SCHEMBL5767363 | 0.85 | LTA4H (0.39) | FGFR1PDE2AMCHR1HRH3KDR | |
| SCHEMBL5767404 | 0.84 | FGFR1 (0.42) | FGFR1SRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235825-B1 | NOVEL BENZOIMIDAZOLE DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | PFIZER PROD INC (US) | 2006-01-25 | — | — | EP | claimed |