Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768634 | 0.90 | CA2 (0.36) | CA2GRM1HTR1AGAAHSD17B10 | |
| SCHEMBL5767727 | 0.84 | CA2 (0.36) | CA2GAAHSD17B10 | |
| SCHEMBL6630732 | 0.83 | HTR1A (0.46) | CA2HTR1AGAAHSD17B10 | |
| SCHEMBL6109572 | 0.83 | HTR1A (0.46) | CA2HTR1AGAAHSD17B10 | |
| SCHEMBL6630209 | 0.83 | HTR1A (0.37) | CA2GRM1ALDH1A1HTR1A | |
| SCHEMBL4821516 | 0.81 | CA2 (0.38) | CA2MAPTALDH1A1HTR1AHSD17B10 | |
| SCHEMBL6630585 | 0.80 | HTR1A (0.39) | CA2ALDH1A1HTR1A | |
| SCHEMBL4335129 | 0.79 | NR3C1 (0.37) | CA2ALDH1A1HTR1AGAAHSD17B10 | |
| SCHEMBL7236260 | 0.78 | CA2 (0.35) | CA2HTR1A | |
| SCHEMBL7240006 | 0.78 | CA2 (0.35) | CA2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381614-B1 | ANTIDEPRESSANT AZAHETEROCYCLYLMETHYL DERIVATIVES OF 2,3-DIHYDRO-1,4-DIOXINO¬2,3-f|QUINOXALINE | WYETH CORP (US) | 2006-08-02 | — | — | EP | claimed |