Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 6/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766061 | 0.84 | DHFR (0.53) | ALDH1A1DHFRSMN1; SMN2CA1CA2 | |
| SCHEMBL5764905 | 0.82 | DHFR (0.48) | ALDH1A1DHFRSMN1; SMN2CA1CA2 | |
| SCHEMBL5766855 | 0.82 | DHFR (0.51) | ALDH1A1DHFRSMN1; SMN2CA1CA2 | |
| SCHEMBL5766891 | 0.81 | ALDH1A1 (0.42) | CACNA1CCACNA1DCACNA1FCACNA1SALDH1A1 | |
| SCHEMBL5765323 | 0.80 | ALDH1A1 (0.40) | CACNA1CCACNA1DCACNA1FCACNA1SALDH1A1 | |
| SCHEMBL5795554 | 0.80 | ALDH1A1 (0.40) | CACNA1CCACNA1DCACNA1FCACNA1SALDH1A1 | |
| SCHEMBL5764332 | 0.78 | ALDH1A1 (0.48) | ALDH1A1DHFRSMN1; SMN2CA1CA2 | |
| SCHEMBL5767457 | 0.78 | ALDH1A1 (0.45) | ALDH1A1DHFRSMN1; SMN2CA1CA2 | |
| SCHEMBL5766842 | 0.78 | ALDH1A1 (0.49) | ALDH1A1DHFRSMN1; SMN2CA1CA2 | |
| SCHEMBL5766803 | 0.78 | ALDH1A1 (0.48) | ALDH1A1DHFRSMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116390-A1 | Hepatitis c virus inhibitors | LG LIFE SCIENCES LTD. (KR) | 2006-06-01 | — | — | US | disclosed |
| EP-1633725-A1 | HEPATITIS C VIRUS INHIBITORS | LG Life Sciences Ltd. (KR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004111013-A1 | HEPATITIS C VIRUS INHIBITORS | LG LIFE SCIENCES LTD. (KR) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116390-A1 | Hepatitis c virus inhibitors | HAVCR2, LIPC, FABP1 | CACNA1C 4703/4885CACNA1D 4868/4885CACNA1F 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.