Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766014 | 0.91 | CHRM3 (0.41) | KCNH2SLC40A1 | |
| SCHEMBL14573148 | 0.90 | KCNH2 (0.47) | KCNH2SLC40A1SLC2A1 | |
| SCHEMBL5774180 | 0.89 | KCNH2 (0.42) | KCNH2SLC40A1SLC2A1 | |
| SCHEMBL6661601 | 0.81 | KCNH2 (0.45) | KCNH2SLC40A1SLC2A1 | |
| SCHEMBL14573161 | 0.81 | SLC40A1 (0.40) | KCNH2SLC40A1SLC2A1 | |
| SCHEMBL5764918 | 0.79 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5657252 | 0.79 | SLC40A1 (0.37) | KCNH2SLC40A1SLC2A1 | |
| SCHEMBL5765881 | 0.77 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5764847 | 0.77 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL5764517 | 0.76 | KCNH2 (0.58) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392686-B1 | BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-10-18 | — | — | EP | claimed |