Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14573161 | 0.91 | SLC40A1 (0.40) | SLC40A1KCNH2 | |
| SCHEMBL5765657 | 0.91 | KCNH2 (0.47) | SLC40A1KCNH2 | |
| SCHEMBL14573148 | 0.81 | KCNH2 (0.47) | SLC40A1KCNH2 | |
| SCHEMBL5657252 | 0.81 | SLC40A1 (0.37) | SLC40A1KCNH2 | |
| SCHEMBL5774180 | 0.80 | KCNH2 (0.42) | SLC40A1KCNH2 | |
| SCHEMBL6661601 | 0.74 | KCNH2 (0.45) | SLC40A1KCNH2 | |
| SCHEMBL5764918 | 0.70 | KCNH2 (0.45) | CHRM3KCNH2 | |
| SCHEMBL5657093 | 0.69 | CHRNA7 (0.47) | SLC40A1 | |
| SCHEMBL5765881 | 0.69 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5764847 | 0.68 | KCNH2 (0.48) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392686-B1 | BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-10-18 | — | — | EP | claimed |